Inspired by a true story, a small independent news crew, made up of reporter Maria and her camera man Tom, investigates a series of unexplained disappearances in a small Midwestern county. The story leads them to the isolated town of Arkham Heights, where they find themselves interviewing Emmett, who possesses an all too intimate knowledge of the details of "The County Line Cannibal" - Cyrus. As Emmett inter-weaves the macabre life tale of Cyrus with the story of his last three victims, Maria comes closer and closer to the greatest story of her life - or what's left of it. Filled with reenacted documentary footage of actual forensic experts, serial killers and police authorities, "Cyrus" presents a simultaneously beautiful and horrific examination of the destructive nature of cause and effect leading to the creation of the most prolific serial killer in the history of the United States.